focal fatty infiltration gallbladder fossa

Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other abusable medications. Astudyconducted by researchers at the Department of General and Thoracic Surgery at the University Hospital Schleswig-Holstein in Kiel, Germany, assessed the DNA of patients with fatty liver disease before and after bariatric surgical treatment for weight loss. Render date: 2023-03-04T12:41:24.974Z Aubin B, Denys A, Lafortune M, Dry R, Breton G. J Ultrasound Med. Privacy Policy. The terms hepatic steatosis and fatty liver disease can be used interchangeably. If you have the fatty liver disease gene, your diet and lifestyle can prevent the expression of these genes. Nonalcoholic fatty liver disease, sometimes called NAFLD, is not connected to alcohol intake. Maintaining a steady calorie deficit is the most effective way to lower your BMI. Important caveat:areas of focal fat sparing may be found adjacent to metastases (see below). No hepatic lesion. Markedly echogenic liver, stats show likely represent diffuse fatty infiltration. 1.1 cm . Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other abusable medications. While diffuse hepatic steatosis is considered common, affecting approximately 25% of the population, focal fatty sparing of the liver is considered a slightly less common pattern across multiple studies 7-9. 98% of physicians recommend this food for liver health which can help manage fatty infiltration of the liver Koseoglu K, Ozsunar Y, Taskin F, Karaman C. Eur J Radiol. Abdom Radiol (NY). 2001;176 (2): 471-4. The goal of this study was to determine by CT the prevalence and characteristics of focal fatty infiltration in children and young adults. Video chat with a U.S. board-certified doctor 24/7 in less than one minute for common issues such as: colds and coughs, stomach symptoms, bladder infections, rashes, and more. The problem arises when the concentration of triglycerides exceeds the normal levels. Finding the right nutrition is an alarming problem over 30 million Americans face who have been diagnosed withliver disease. Of 218 children and young adults, 20 (9.2%) met the CT criterion for focal fatty infiltration of the liver. An individuals personality like introversion or open-mindedness is highly influenced by both genes and the environment. Sohn J, Siegelman E, Osiason A. Int J Chron Obstruct Pulmon Dis. Eating an abundance of fruits and veggies is vital for protecting your liver from fatty liver progression and worsening liver conditions. Bethesda, MD 20894, Web Policies 8600 Rockville Pike Exercising more frequently helps reduce systemic inflammation while also encouraging weight loss and a healthy metabolism. Although fatty infiltration of the liver can remain stable for many years, if left untreated it can progress to cirrhosis. Hepatomegaly. 2015 Dec;205(6):1167-72. doi: 10.2214/AJR.15.14724. Porcelain gallbladder. These are the areas prone to altered hepatic blood flow with systemic . Numerous other tests can confirm the presence of fat within the liver. diffuse hepatic steatosis. In the early stages, fatty liver disease is not life-threatening and may not show any noticeable symptoms. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. NAFLD encompasses a spectrum of conditions, ranging from benign hepatocellular steatosis to inflammatory nonalcoholic . Recognition of this finding is important to prevent the erroneous belief that the region of sparing is itself a mass. FOIA By using our website, you consent to our use of cookies. I was discharged from the hospital after a biliary stent was placed due to bile leakage, and my biloma was not drained. Most patients with In addition to fatty liver disease, an echogenic liver might accompany other root causes. HealthTap uses cookies to enhance your site experience and for analytics and advertising purposes. Fatty infiltration of the liver is also referred to as fatty liver disease, which is also known as Steatohepatitis. If the gallbladder has been removed, Incidental observation of fatty liver with fatty sparing around the gallbladder fossa in ct trauma analysis? Small area of focal fat sparing adjacent to the gallbladder fossa. Echogenicity describes how readily sound waves bounce off tissues during an ultrasound examination, which is conducted by a specialist in radiology. 022H Asymmetric Hypertrophic Obstructive Cardiomyopathy. Focal hepatic steatosis. Research has found that adding just as little as 30 minutes of physical activity to your daily routine can go a long way. diffuse fatty infiltration liver. A review of the literature and 19 new cases. 2017 May;42(5):1374-1392. doi: 10.1007/s00261-016-1002-6. A healthier metabolism may help your body clear fat from the liver. This is called congestive hepatomegaly. Steer clear of added sugars, saturated fat, trans fat, and artificial preservatives. (2006) Radiographics : a review publication of the Radiological Society of North America, Inc. 26 (6): 1637-53. congenital malformations and anatomical variants. According to the American Liver Foundation, fatty liver disease occurs when more than 5% - 10% of the liver is made up of fat. [2] How do I know if I have fatty infiltration of the liver? Bothcoffeeand green tea are liver-friendly drinks that you can incorporate into your daily routine. Definition. Analysis of prostaglandin-endoperoxide synthase-2 gene polymorphisms and risk. Ultrasound features only become apparent when the amount of fat reaches 15-20%. [1] Nonalcoholic fatty liver disease (NAFLD) is evidence of hepatic steatosis (imaging or histologic) in the absence of secondary causes of hepatic fat accumulation, such as significant alcohol consumption. Focal fat sparing near GB fossa. For example, a naturally introverted child may become more extroverted over time in response to positive experiences with family and peers. Focal sparing appears as hypo echoic against Echogenic back ground "geographic" nature, often adjacent to gallbladder fossa and falciform ligament Diffuse fatty infiltration may mask other focal lesions Seen in excessive alcohol consumption, diabetes, obesity and hyper lipidemia Focal sparing is more common than focal steatosis 10-15% (hepatic Detection is by either ultrasound study or a CT scan.. Exercise promotes weight loss and cardiovascular health. Eating a diet high in high-quality protein is often recommended for fatty liver disease. Focal adenomatous chg seen in the epithelium, does not involve the margin on gall bladder pathology report, what does it mean? Fultz PJ, Hampton WR, Skucas J, Sickel JZ. Del pilar fernandez M, Bernardino ME. Find out more about the Kindle Personal Document Service. Yoshikawa J, Matsui O, Takashima T, Sugiura H, Katayama K, Nishida Y, Tsuji M. AJR Am J Roentgenol. The finding itself, however, is non-specific and can be found in a wide range of . When you are not eating the fat is broken down and u fossa is simply an anatomic description of the location of the gallbladder on the liver. Disclaimer. Focal hepatic steatosis, also known as focal hepatosteatosis or (erroneously)focal fatty infiltration,represents small areas of liver steatosis. 2019 Dec 31;14:3053-3061. doi: 10.2147/COPD.S233834. eCollection 2021. Liver cirrhosis may be accompanied by symptoms like loss of appetite, muscle wasting, easily bruising, unintentional weight loss, jaundice, weakness, and fatigue. Idilman IS, Ozdeniz I, Karcaaltincaba M. Hepatic Steatosis: Etiology, Patterns, and Quantification. Diffuse liver changes affect the entire organ. Your DNA an abbreviation short for deoxyribonucleic acid is a code that makes you human and determines your individual traits. In case of hepatic steatosis parts of the liver are left out or are affected to a lesser extent (zonal fatty sparing) just as focal fatty infiltration can occur in a normal healthy liver. Fatty infiltration of the liver is also referred to as fatty liver disease, which is also known as Steatohepatitis. How can I prevent fatty infiltration of the liver? 1. (2011) Insights into imaging. (give in NS) Has a high pH, will cause severe local tissue necrosis in cases of infiltration (g ive antecubital or central line) Elevate limb, apply d ry heat and cool compresses after extravasation Side effects Hypotension Heart blocks . LIVER: "There is diffuse low-density throughout the liver compatible fatty infiltration. Steatosis may be diffuse, geographic, focal, subcapsular, multifocal or perivascular. The authors here describe a number of imaging features which together are distinctive and may be diagnostic of focal fatty infiltration of the liver. An echogenic liver is an ultrasound reading that indicates a higher level of fat in the liver. Immunotherapy is based on manipulation of the immune system in order to act against tumour cells, with growing evidence especially in melanoma patients. Such micronutrients play a role in reversing fatty liver disease, improving insulin sensitivity, and lowering blood pressure. Subsequently, the insulin blocks the oxidation of free fatty acids in the hepatocytes and leads to preferential esterification of triglycerides which then accumulate within the cell . The role of CT in the diagnosis of fatty liver is well established. Right side pain under ribcage, spreading to back throughout the day. In focal fatty infiltration, the normal hepatic vessels traverse the area of decreased attenuation, a finding not usually present in malignancy. Conversely, you dont have to have the fatty liver disease gene to develop fatty liver disease. A magnetic resonance imaging (MRI) test uses radio waves to reveal detailed information about hepatic fat levels. This is why Amsety has designed a delicious yet nutrient-dense formula in a bar formulation. Fatty liver deposition is a very common finding but it has many atypical patterns of distribution that can represent diagnostic pitfalls. As mentioned previously, lifestyle modifications such as adding exercise into your daily routine, limiting toxins and unhealthy food can treat, prevent or even reverse non-alcoholic fatty liver disease. There is a increased hepatic echogenicity which may be fatty infiltration. tous infiltration and 16 nodes of the ileum and 2 of the jejunum were reactive. To learn more, please visit our. Limiting alcohol is vital for protecting your liver from fatty liver disease progression or liver disease. Knowing the anatomy and the normal imaging appearance of these organs in the post-menopausal woman is fundamental to recognize physiological post-menopausal changes and to identify findings that can be normal in the reproductive years but pathological . Hepatic pseudolesion: appearance of focal low attenuation in the medial segment of the left lobe at CT arterial portography. Small collections often get absorbed, If not they can be drained by a needle . Triglycerides occupy 5% of the liver weight under normal conditions. 2004;183 (3): 721-4. When focal fatty infiltration of the liver has the appearance of a small nodule, it can be confused with a more serious hepatic abnormality [6,7,8,9].Because a high percentage of CT examinations in children are performed to evaluate tumor progression, knowledge of the CT appearance of focal fatty infiltration of the liver is critical for accurate interpretation. No hepatic lesion. Had gallbladder removed 3 weeks ago. Find out more about saving content to Google Drive. They are designed based on the dietary restrictions of liver patients. Nausea, Hemorrhoids. Alt 142 ast 77 are these bad? 1987 Sep;149(3):491-4. doi: 10.2214/ajr.149.3.491. The term 'fatty infiltration of the liver' is often erroneously used to describe liver steatosis. 5. (1)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381829/, (2)https://www.ncbi.nlm.nih.gov/pubmed/23931760/, Refractory Ascites: Diagnosis and Treatment, NAFLD Diet Guidelines and Recommendations, bariatric surgical treatment for weight loss, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381829/, https://www.ncbi.nlm.nih.gov/pubmed/23931760/. what could this mean? CT scan results: LIVER: "There is diffuse low-density throughout the liver compatible fatty infiltration. It isn't good or bad. At the time the article was last revised Daniel J Bell had Castro MA, Ouzounian JG, Colletti PM, Shaw KJ, Stein SM, Goodwin TM. What Your Liver Size Says About Your Health, fatty liver disease can be managed and possibly reversed, alcohol dependence, avoid going cold turkey with alcohol, First Liver Transplant: Its Success and its Effect to Future Surgeries, Is an Enlarged Liver Dangerous? To save this book to your Kindle, first ensure coreplatform@cambridge.org Occasionally, focal sparing is nodular and located elsewhere in the liver. AJR Am J Roentgenol. on the Manage Your Content and Devices page of your Amazon account. Content may require purchase if you do not have access. Focal fatty sparing is per se an asymptomatic and benign phenomenon. Nodular or mass-like lesions in a diffusely fatty liver that are only well seen on out of phase gradient-echo MR imaging, when visualized during an MR study that includes T2-weighted and dynamic gadolinium-enhanced sequences, should suggest focal fatty sparing.It is possible that true primary or secondary tumors in a diffusely fatty liver could also be better seen on opposed phase imaging, but such lesions would almost certainly demonstrate increased T2 signal intensity or altered vascularity relative to the liver parenchyma on dynamic gadolinium-enhanced images. Is it dangerous, can it be prevented, and how do you know if you have it? ADVERTISEMENT: Supporters see fewer/no ads. Published online by Cambridge University Press: Primary lymphoma of the liver, gallbladder, and extrahepatic bile ducts or secondary involvement of these organs by leukemia is exceedingly rare. Hepatic metastasis disguised as fat spared area in the background of fatty liver: Detection on FDG PET/CT. 2014 Oct 24;9(10):e111283. As you lose weight, excess fat will disappear from adipose tissue and your liver. Tips for Recovery from Alcoholic Fatty Liver Disease and Signs Your Liver Is Healing, Best Vegan Meal Plan for Fatty Liver Disease, High Protein Vegan Recipes You Should Try, Bariatric Surgery Diet Pre Op and Post Op: What You Should Know, New Year New Me: How to Strive for Weight Loss, What You Need to Know About High Functioning Depression and How to Manage It. Harder tissue suggests the presence of fat or inflammatory damage in the liver. It is also crucial to get the essential vitamins and minerals your body needs. Venkatesh SK, Hennedige T, Johnson GB, Hough DM, Fletcher JG. Sometimes a part of the liver tissue may become hypodense as compared to the nearby tissue due to focal fatty changes or due to primary or secondary tumors. Any collection in that area may be due to leakage ( a small collection of 10-15ml is not unusual after GB surgery). Exercising regularly, cutting out processed foods, and getting a balance of healthy fats, carbs, and essential amino acids are key when it comes to preventing and reversing nonalcoholic hepatic steatosis. As the name suggests, elastography can assess the texture of liver tissue. It was suggested that differences in the dynamics of enhancement in the vascular phase of CEUS were influenced by the fat deposits in the target lesion, the surrounding liver parenchyma, and . Requires both in- and out-of-phase imaging and contrast to adequately assess 1. Occasionally, hepatic steatosis can present a random, irregular geographic configuration [ 1 ]. Egg whites, chicken breast, and low-fat dairy are excellent sources of high-quality protein. Other traits, such as personality, are much more complex and described as polygenic traits since they are influenced by a large number of different genes. is added to your Approved Personal Document E-mail List under your Personal Document Settings HHS Vulnerability Disclosure, Help Viglino D, Martin M, Almeras N, Desprs JP, Coxson HO, Ppin JL, Vivodtzev I, Maltais F; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators. 1993 Jul-Aug;17(4):590-5. is there a problem of fatty lever? Please enable it to take advantage of the complete set of features! 2 (5): 533-538. Tom WW, Yeh BM, Cheng JC et-al. good luck. Shapiro MA, et al. Keep in mind that developing liver fibrosis and cirrhosis also increases the risk of developing liver cancer. how long does it last? Cookie Notice Focal fatty sparing around the gallbladder is also probably related to . 1986 Jan;59(697):25-8. doi: 10.1259/0007-1285-59-697-25. . Saturated fat negatively impacts metabolism and also increases the risk of heart disease. Educational text answers on HealthTap are not intended for individual diagnosis, treatment or prescription. eCollection 2014. Pathological analysis. The worst part is my mom just left ICU from a Liver transplant surgery (successful so far). We often found a high attenuation region around the . The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Top answers from doctors based on your search: Created for people with ongoing healthcare needs but benefits everyone. Gallbladder surgery 5 days ago. 026H SLE Pulmonary Hypertension Libman Sacks. In some cases, your physician may prescribe medications like metformin and statins to help concurrent metabolic conditions like insulin resistance and high cholesterol. Mild diffuse fatty liver infiltration liver enzymes 2 weeks ago was ast 50 alt 110 now they r ast 77 alt 142 does this mean its worse or maybe cirrhosis? Fatty liver disease is characterized by the accumulation of fat within liver cells. Radiographics. To effectively prevent and reverse fatty liver disease, its important to understand the causal factors fueling its development. So, what happens when we consume excess sugar? Whenever the word . Convert K82.8 to ICD-9-CM. could this be remanent gallbladder left over? By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. Focal fat deposition can occur in characteristic areas of the liver: most commonly adjacent to the falciform ligament, at the porta hepatis, and about the gallbladder fossa. What is some focal fatty sparing in the right hepatic lobe and adjacent to the gallbladder fossa, Small hypoechoic areas with a geographic configuration are seen adjacent to the gallbladder and are compatible wiht focal sparing, What does fatty infiltration of the liver mean, What does thickening of the gallbladder wall mean, What does mild fatty infiltration of the liver mean, What does diffuse fatty infiltration of the liver mean, What does it mean minimal fluid is seen cul de sac. Unable to process the form. The superior part of the duodenum, hepatic flexure and proximal transverse colon, are posteriorly related to it. CT appearance of focal fatty infiltration of the liver. **Is a 4 cm focal fatty infiltration of the liver a very serious matter? . Thickening of the gallbladder wall is a relatively frequent finding at diagnostic imaging studies. Check for errors and try again. NASH describes a state of chronic inflammation in the liver. Persistent isoenhancement on contrast enhanced ultrasound compared with liver parenchyma. An official website of the United States government. So, leftover sugar is converted into fat and stored throughout the body. Therefore the severity of fatty infiltration of the liver can be quite dangerous if left untreated. During the early stages, fatty liver disease often exhibits no symptoms. This condition is known as fatty infiltration of liver. 2017 Jun;42(6):1667-1678. doi: 10.1007/s00261-017-1049-z. . Br J Radiol. AJR Am J Roentgenol. eCollection 2019. Find out more about saving content to Dropbox. Saturated fat essentially clogs up insulin receptors, meaning that insulin becomes less effective. By using our website, you consent to our use of cookies. However, the body cant use all of the sugar at once. Instead, nonalcoholic fatty liver disease arises from the chronic consumption of unhealthy foods. Symptoms may worsen during this time. Fatty liver disease is a very common condition, with a prevalence of 20-30% in the adult population [ 1] and 70% in diabetes patients [ 2 ]. Both lymphoid and myeloid leukemia have been reported to involve the gallbladder. Here are a few examples: An internist will be involved in treating fatty liver disease by serving as a point of contact for all of your health professionals. Such atypical nodular focal fatty sparing may result in lesions that are hypoechoic at ultrasound and hyperdense at CT and may be mistaken for metastases or other tumors (Figures 19.1 and 19.2) [24]. r/o Focal fat sparing. A 29-year-old female patient was referred by her general gynecologist for further imaging with suspected right-sided ovarian endometrioid cyst. If a patient's findings met the CT criterion for focal fatty infiltration of the liver, all previous abdominal CT and MR imaging examinations performed for that patient were reviewed to assess the evolution of focal fatty infiltration of the liver. small area of probable focal fat sparing adjacent to the gallbladder fossa. Reference article, Radiopaedia.org (Accessed on 04 Mar 2023) https://doi.org/10.53347/rID-1344, {"containerId":"expandableQuestionsContainer","displayRelatedArticles":true,"displayNextQuestion":true,"displaySkipQuestion":true,"articleId":1344,"questionManager":null,"mcqUrl":"https://radiopaedia.org/articles/focal-hepatic-steatosis/questions/1098?lang=us"}, View Frank Gaillard's current disclosures, see full revision history and disclosures, World Health Organization 2001 classification of hepatic hydatid cysts, recurrent pyogenic (Oriental) cholangitis, combined hepatocellular and cholangiocarcinoma, inflammatory myofibroblastic tumor (inflammatory pseudotumor), portal vein thrombosis (acute and chronic), cavernous transformation of the portal vein, congenital extrahepatic portosystemic shunt classification, congenital intrahepatic portosystemic shunt classification, transjugular intrahepatic portosystemic shunt (TIPS), transient hepatic attenuation differences (THAD), transient hepatic intensity differences (THID), total anomalous pulmonary venous return (TAPVR), hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease), cystic pancreatic mass differential diagnosis, pancreatic perivascular epithelioid cell tumor (PEComa), pancreatic mature cystic teratoma (dermoid), revised Atlanta classification of acute pancreatitis, acute peripancreatic fluid collection (APFC), hypertriglyceridemia-induced pancreatitis, pancreatitis associated with cystic fibrosis, low phospholipid-associated cholelithiasis syndrome, diffuse gallbladder wall thickening (differential), focal gallbladder wall thickening (differential), ceftriaxone-associated gallbladder pseudolithiasis, biliary intraepithelial neoplasia (BilIN), intraductal papillary neoplasm of the bile duct (IPNB), intraductal tubulopapillary neoplasm (ITPN) of the bile duct, multiple biliary hamartomas (von Meyenburg complexes), drugs (amiodarone, methotrexate, chemotherapy), inability to visualize the portal vein walls (as the parenchyma is as bright as the wall), decreases by 1.6 HU per mg of fat in each gram of liver, liver and spleen should normally be similar on delayed (70 seconds) scans, earlier scans are unreliable as the spleen enhances earlier than the liver (systemic supply rather than portal). Its helpful to have a workout plan that you enjoy so you can stick to it and see the results you want. Ultrasound one year ago said diffuse fatty infiltration of the liver, now it says fatty infiltration of the liver with focal fatty sparring, meaning? after 1 month, the patient visited the emergency service with abdominal pain, a fever of 38.4C, with no functioning Multiple liver lesions in an immunosuppressed patient: is infection always the answer. If you cons What does diffuse fatty infiltration of the liver mean? To save content items to your account, For potential or actual medical emergencies, immediately call 911 or your local emergency service. Also, experts do not exclude parasites or . Conclusion. Hepatobiliary contrast agents such as gadoxetate disodiumcan show greater delayed uptake and biliary excretion when compared to the fatty liver due to a greater concentration of functioning hepatocytes 4. diffuse hepatic steatosis. Food can help you change how your DNA is expressed and following a hepatic steatosis diet can help reverse fat accumulation in your liver. Amsety does not offer any medical diagnosis or treatment advice and our products are not intended to diagnose, The liver is a resilient and adaptive organ and is able to heal, especially when fatty liver disease is treated in early stages. Halvorsen RA, Korobkin M, Ram PC, Thompson WM. If the lesion is hypoechoic compared to a background fatty liver (hyperechoic), and in a typical location for focal fatty sparing (adjacent to GB fossa, segment 4B, . Constipation. Educational text answers on HealthTap are not intended for individual diagnosis, treatment or prescription. The liver does not usually store fat. Has data issue: true I had a lap chole 2 months ago, i'm still having ruq pain. Dishing out money on an expensive gym membership is not the only way to lose weight and get the exercise you need. Before we go any further, its essential first to address what it means to have an echogenic liver. Focal fatty sparing is usually geographic in shape and located near the gallbladder fossa and porta hepatis [1]. sharing sensitive information, make sure youre on a federal Chronic oxidative stress and inflammation leads to liver damage. At the time the article was created Frank Gaillard had no recorded disclosures. Available in two delicious flavors of Dark Chocolate and Peanut Butter, Amsety Bars contain a unique Super 16 Vitamin & Mineral Mixwith the essential vitamins and minerals for optimal liver health. Focal fat may simulate a liver tumor; however, the area of involvement has a density characteristic of fat. When an atypical form of fatty liver deposition is suspected on ultrasound or CT, MRI may be used to confirm the diagnosis . 9. However, the patient may be symptomatic from the abnormally increased fattiness of the remainder of the liver. Progressed forms of fatty liver disease include: Determining the causes of hepatic steatosis is crucial to successfully treating and reversing the condition, in order to prevent progression to more serious stages. Diet and lifestyle can influence your genes for better or for worse. . Fatty infiltration is generally a benign process which often resolves on its o. 4. told results were norma. Sites of predilection are perivascular and gallbladder fossa in. 8600 Rockville Pike demonstrate circumferential irregular small Crohn's disease bowel wall thickeningtumour with adjacent fat infiltration (white Insights . It is the most common. Lupsor M, Badea R. Imaging diagnosis and quantification of hepatic steatosis: is it an accepted alternative to needle biopsy? Patients are usually asymptomatic and present with "transaminitis" a term which is synonymous and used interchangeably with elevated liver enzymes and or transaminasemia, specifically . Individual calorie needs are determined by your individual metabolism, activity level, and any specific needs. Sonographic evaluation of the abdomen was performed and is compared to the prior examination of 02/01/02 (gallbladder attack at 7 months pregnancy with 4th child) Increased echogenicity of the hepatic parenchyma suggests a mild to moderate degree of diffuse fatty infiltration.

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focal fatty infiltration gallbladder fossa